By Hiroshi Mitsumoto MD
Amyotrophic Lateral Sclerosis offers the main finished, clinically-focused details on ALS (Lou Gehrig's sickness) in print. the 3 authors, well known for his or her paintings during this zone, supply cohesive and balanced insurance of this syndrome, together with the background, scientific good points, pathology and pathogenesis, therapy and administration of ALS. To facilitate knowing, every one bankruptcy is greater through accomplished tables and figures, in addition to distinct bankruptcy summaries.
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39. Kurland, LT and Mulder, DW: Epidemiologic investigations of amyotrophic lateral sclerosis. Familial aggregation indicative of dominant inheritance. Neurology 5:182-196, 1955. 40. Lawyer, JR, Netsky, T, and Netsky, MG: Amyotrophic lateral sclerosis. Arch Neurol Psychiatry 69:171-192, 1953. 41. Leyden, EV: Uber progressive Bulbarparalysie. Arch Psychiatr i:648; ii:657; iii:338, 1870. 42. Luys, J: Atrophie musculaire progressive. Gaz Med Fr 3 & 4: 505, 1860. 43. Mackay, RP: Course and prognosis in amyotrophic lateral sclerosis.
Epidemiology 21 Figure 2-2. Prevalence rates of ALS reported from 1964 until 1994 in various countries (except in the Western Pacific) are diagrammed according to decreasing frequency. Reference numbers of the respective studies are indicated in parentheses. Figure 2-3. Age-specific incidence of sporadic ALS for males and females is seen to increase until the eighth decade, with a dramatic decline after a peak between 55 and 75 years of age. Sex-related incidence is higher in males, although this is less pronounced over 65 years of age.
16 Introduction to ALS 28. Gowers, WR: A Manual of Diseases of the Nervous System, vol 1, ed 3. Plakiston, Philadelphia, 1899, pp 531-558. 29. Greenfield, JG: Amyotrophic lateral sclerosis. In Greenfield, JG, Blackwood, W, McMenemey, WH, et al (eds): Neuropathology. Arnold, London, 1958, pp 545-548. 30. Haymaker, W and Schiller, F: The Founders of Neurology, ed 2. Charles C Thomas, Springfield, IL, 1970. 31. Heitzman, D, Wilbourn, A, and Mitsumoto, H: A retrospective study examining the clinical and electrodiagnostic features of patients with bulbar-onset amyotrophic lateral sclerosis.